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Ming-Na Wen,Lauren Tom,Tamlyn Tomita,Rosalind Chao,Kiều Chinh,France Nuyen,Tsai Chin,Lisa Lu,Chao Li Chi,Melanie Chang,Victor Wong,Irene Ng,Christopher Rich,Russell Wong,Michael Paul Chan,Philip Moon,Andrew McCarthy,Fen Tian,Vivian Wu,Jack Ford
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Aziz Ansari
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Leslie Nielsen,Kelly Lynch,Matt Keeslar,Nick Chinlund,Stephen Tobolowsky,Ernie Hudson,Jennifer Garner,Malcolm McDowell,Miguel Ferrer,L. Harvey Gold,Art Irizawa,John Tierney,Terence Kelly,Dolores Drake,Frank C. Turner,Robert Metcalfe,Jerry Wasserman
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Martin Lawrence,Tim Robbins,John C. McGinley,Giancarlo Esposito,Kelly Preston,Michael McKean,Rebecca Gayheart,Irma P. Hall,Steve Oedekerk,Susan Barnes,Samaria Graham,Penny Bae Bridges,Randy Oglesby,Caroline Keenan,J.J. Boone,Kim Kim,Marcus T. Paulk
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Whoopi Goldberg,Ted Danson,Will Smith,Nia Long,Paul Rodríguez,Jennifer Tilly,Peggy Rea,Clyde Kusatsu,David Bowe,Jeffrey Joseph,Rawley Valverde,Fred Mancuso,Charlene Fernetz,Shawn Levy,Lu Leonard,Joe Lerer,Janice Edwards,Michael McFall,Phyllis Avery
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Sandra Bullock,Melissa McCarthy,Demián Bichir,Marlon Wayans,Michael Rapaport,Jane Curtin,Spoken Reasons,Dan Bakkedahl,Taran Killam,Michael McDonald,Thomas F. Wilson,Peter Weireter,John Ross Bowie,William Xifaras,Cary 'Big Shug' Guy
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Jamie Dornan,Guillaume Canet,Mark Strong,Jason O'Mara,Michael McElhatton,Mikael Persbrandt,Danny Sapani,Fionn O'Shea,Fiona Glascott,Emmanuelle Seigner,Conor Quinlan,Sam Keeley,Conor MacNeill,Luc Van Gunderbeeck,Jordan Mifsud,Charlie Kell
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Harrison Ford,Gary Oldman,Glenn Close,Wendy Crewson,Liesel Matthews,Paul Guilfoyle,Xander Berkeley,William H. Macy,Dean Stockwell,Tom Everett,Jürgen Prochnow,Donna Bullock,Michael Ray Miller,Carl Weintraub,Elester Latham,Elya Baskin
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Dylan O'Brien,Kaya Scodelario,Thomas Brodie-Sangster,Ki Hong Lee,Rosa Salazar,Giancarlo Esposito,Will Poulter,Jacob Lofland,Patricia Clarkson,Aidan Gillen,Walton Goggins,Dexter Darden,Katherine McNamara,Nathalie Emmanuel,Barry Pepper,Dylan Smith
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Keke Palmer,Cory Hardrict,Eric D. Hill Jr.,Quincy Brown,Nafessa Williams,Logan Browning,Teyana Taylor
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Chris D'Elia
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Steve Carell,Kristen Wiig,Trey Parker,Miranda Cosgrove,Dana Gaier,Nev Scharrel,Steve Coogan,Julie Andrews,Jenny Slate,Pierre Coffin,Chris Renaud,Andy Nyman,Michael Beattie,Adrian Ciscato,Brian T. Delaney,Ken Daurio,Lori Alan,Carlos Alazraqui
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Jeff Daniels
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Madonna,Antonio Banderas,Jonathan Pryce,Jimmy Nail,Victoria Sus,Julian Littman,Olga Merediz,Laura Pallas,Julia Worsley,María Luján Hidalgo,Servando Villamil,Andrea Corr,Alan Parker,Adrià Collado,Gary Brooker,Maite Yerro,Mark Ryan,Peter Polycarpou
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Ken Berry,Sandy Duncan,Harry Morgan,Roddy McDowall,McLean Stevenson,Jesse White,Alan Young,Hans Conried,Ronnie Schell,James Hampton,Howard Platt,William Prince,Ralph Manza,Tom Pedi,Hank Jones,Rick Hurst,John Alderson,Tiger Joe Marsh,Arnold Soboloff
동물의 얘기를 알아듣는 독특한 능력을 타고난 존 두리틀(에디 머피)은 어릴 적 아버지에게 호된 야단을 맞고는 자신의 능력을 까맣게 잊고 성장한다. 어느날 두리틀은 러키라는 개가 하는 말을 알아듣고는 혼란에 빠지는데 이 일을 안 동네의 아픈 짐승들이 모두 두리틀의 집으로 몰려온다. 두리틀은 처음엔 당황하지만 자신이 동물들에게 도움이 된다는 사실에 의사로서의 보람을 새롭게 느낀다. 한편 마크, 진과 함께 운영하던 병원을 의료업계 재벌 캐넷사가 인수하려 하자 두리틀은 처음엔 돈을 벌수 있는 기회라며 좋아한다. 하지만 동물들과 얽히는 과정에서 두리틀은 의사로서 타성에 젖은 자신을 반성하게 된다.